What is meant by the foreign protein load of a botulinum toxin product? How high is the foreign protein?

The foreign protein load is the content of bacterial proteins (these include the neurotoxin, complexing proteins, bacterial cell residues, etc.) that are recognised as “foreign” by the human organism and can trigger an immune reaction.

 

Foreign protein load of the different type A products:

 

XEOMIN®: approx. 0.6 ng/100 units

 

Botox®: approx. 5 ng/100 units

 

Dysport®: approx. 4 ng/400 units

 

Therefore, XEOMIN® has the lowest foreign protein load. 

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